EGFR Gene Mutation Detection Kit
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The AmoyDx EGFR Mutation Test Kit is a superior sensitive and selective assay for the detection of the most common somatic mutations in the Epidermal Growth Factor Receptor (EGFR) gene.
EGFR gene mutation relates to the drug response of Iressa (Gefitinib) and Tarceva (Erlotinib). The cancer patients with mutant EGFR genes are sensitive to Iressa and Tarceva, whereas the patients without EGFR mutations cannot be benefit from the treatments. However, the EGFR T790M mutation causes drug resistance.
The Eurpean Drug Administration Organization requires the detection of EGFR gene mutation prior to the usage of Iressa on NSCLC patients. The NCCN 2009 recommended the usage of Tarceva on NSCLC patients with EGFR mutations. Two researches published on The New England Journal of Medicine states that the EGFR mutation detection should be operated prior to the employment of Iressa and Tarceva
Intended Use: For research purpose use only. To aid doctors to identify colorectal cancer patients who are more likely be benefit from anti-EGFR therapies such as Iressa and Tarceva.
Technological Principles: The EGFR mutation kit employs real-- time PCR format combined with patent technology-“mutation specific amplification technology”, to detect mutations in DNA samples, which reaches the high specificity and high sensitivity of the rare mutation detection.
The EGFR mutation kit enables detection of the following mutations against a background of wild-type genomic DNA.
AmoyDx EGFR Mutation Test Kits are available in different sizes:
|Product Name||Size (test/Kit)||Storage||Cat. No.|
|EGFR 29 Mutations Detection Kit||12t||-20 ° C||ADx-EG01|