mouse anti- Human Myoglobin monoclonal Antibody

Product Type: Monoclonal antibodies
Product Name: mouse anti- Human Myoglobin monoclonal Antibody
Size: 100ug
Code: CSB-MA079101A0m
Immunogen: Recombinant Human Myoglobin protein
Raised in: Mouse
Species Reactivity: Human
Spectificity: specific for native and denatured forms
Tested Applications: ELISA, WB, and other possible application
Relevance: Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal
Clonality: monoclonal
Isotype: IgG2a
Purity: >95% by Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: liquid
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles
References: [1] Karabay O, Tuna N, Ogutlu A, Gozdas HT.High ferritin and myoglobin level in legionella pneumonia: a case report and review of literature. Indian J Pathol Microbiol. 2011 Apr-Jun;54(2):381-3. [2] Liu M, Hou M, Liu LP, Zhang CX, Zhao CY, Ma CJ, Zhong SN, Song Y.The value of determination of serum myoglobin in estimation of degree of illness and prognosis of patients with sepsis in Xining area. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Feb;23(2):85-7. [3] Orak M, Ustünda? M, Gülo?lu C, Gökhan S, Alyan O.Relation between serum Pro-Brain natriuretic peptide, myoglobin, CK levels and morbidity and mortality in high voltage electrical injuries. Intern Med. 2010;49(22):2439-43. Epub 2010 Nov 15. [4] Kristiansen G, Hu J, Wichmann D, Stiehl DP, Rose M, Gerhardt J, Bohnert A, Ten Haaf A, Moch H, Raleigh J, Varia MA, Subarsky P, Scandurra FM, Gnaiger E, Gleixner E, Bicker A, Gassmann M, Hankeln T, Dahl E, Gorr TA.Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? J Biol Chem. 2011 Sep 19. [5] Hendgen-Cotta UB, Flögel U, Kelm M, Rassaf T.Unmasking the Janus face of myoglobin in health and disease. J Exp Biol. 2010 Aug 15;213(Pt 16):2734-40. [6] Liu Y.Radioimmunoassay and immunohistochemical study of myoglobin in neuromuscular diseases. Zhonghua Yi Xue Za Zhi. 1992 Mar;72(3):144-6, 190. [7] Lovece S, Kagen LJ.Sensitive rapid detection of myoglobin in serum of patients with myopathy by immunoturbidimetric assay. J Rheumatol. 1993 Aug;20(8):1331-4. [8] Nicholson LV.Serum myoglobin in muscular dystrophy and carrier detection. J Neurol Sci. 1981 Sep;51(3):411-26. [9] Mula-Abed WA, Al-Sinani SS, Al-Hashmi HS.Serum myoglobin in patients with thyroid dysfunction. Sultan Qaboos Univ Med J. 2009 Apr;9(1):37-41. Epub 2009 Mar 16. [10] Goksu E, Oktay C, Kilicaslan I, Kartal M.Seizure or syncope: the diagnostic value of serum creatine kinase and myoglobin levels. Eur J Emerg Med. 2009 Apr;16(2):84-6. [11]Kagen LJ. Myoglobinemia and myoglobinuria in patients with myositis. Arthritis Rheum. 1971 Jul–Aug;14(4):457–464. [12] Kasaoka S, Todani M, Kaneko T, Kawamura Y, Oda Y, Tsuruta R, Maekawa T.Peak value of blood myoglobin predicts acute renal failure induced by rhabdomyolysis.J Crit Care. 2010 Dec;25(4):601-4. [13] Rodríguez-Capote K, Balion CM, Hill SA, Cleve R, Yang L, El Sharif A.Utility of urine myoglobin for the prediction of acute renal failure in patients with suspected rhabdomyolysis: a systematic review.Clin Chem. 2009 Dec;55(12):2190-7. Epub 2009 Oct 1. Review. [14] Moselhy SS, Demerdash SH.Serum free L-carnitine in association with myoglobin as a diagnostic marker of acute myocardial infarction.Clin Biochem. 2009 Jan;42(1-2):78-82. Epub 2008 Sep 30.
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