Rabbit anti- human Ganglioside GM2 activator polyclonal Antibody

Product Type: Polyclonal antibody
Product Name: Rabbit anti- human Ganglioside GM2 activator polyclonal Antibody
Alias: GM2A,Cerebroside sulfate activator protein,GM2-AP,Shingolipid activator protein 3,SAP-3
Size: 100ug
Code: CSB-PA02375A0Rb
Species:
Immunogen: Recombinant human Ganglioside GM2 activator protein
Raised in: Rabbit
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB, IHC
Application Notes:
Relevance: Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galact
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
References: [1] "Isolation and expression of a full-length cDNA encoding the human G-M2 activator protein."Xie B., McInnes B., Neote K., Lamhonwah A.-M., Mahuran D.Biochem. Biophys. Res. Commun. 177:1217-1223(1991) [2] "Characterization of full-length cDNAs and the gene coding for the human GM2 activator protein."Klima H., Tanaka A., Schnabel D., Nakano T., Schroeder M., Suzuki K., Sandhoff K.FEBS Lett. 289:260-264(1991) [3] "Evidence for two cDNAs encoding human GM2-activator protein."Nagarajan S., Chen H.C., Li S.C., Li Y.T., Lockyer J.Biochem. J. 282:807-813(1992)