Rabbit anti- human High mobility group protein B1 polyclonal Antibody, HRP conjugated

Product Type: Polyclonal antibody
Product Name: Rabbit anti- human High mobility group protein B1 polyclonal Antibody, HRP conjugated
Alias: HMG1,HMGB1,High mobility group protein 1,HMG-1
Size: 100ug
Code: CSB-PA01604B0Rb
Species:
Immunogen: Recombinant human High mobility group protein B1 protein
Raised in: Rabbit
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC
Application Notes:
Relevance: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombinati
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: HRP conjugated
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
References: [1] "A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1."Wen L., Huang J.K., Johnson B.H., Reeck G.R.Nucleic Acids Res. 17:1197-1214(1989) [2] "The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13."Ferrari S., Finelli P., Rocchi M., Bianchi M.E.Genomics 35:367-371(1996) [3] "Expression of high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa."Xiang Y.-Y., Wang D.-Y., Tanaka M., Suzuki M., Kiyokawa E., Igarashi H., Niato Y., Shen Q., Sugimura H.Int. J. Cancer 74:1-6(1997)