Goat anti-human Cystatin-C protein polyclonal Antibody

Product Type: Polyclonal antibody
Product Name: Goat anti-human Cystatin-C protein polyclonal Antibody
Alias: Cystatin-3 Gamma-trace Neuroendocrine basic polypeptide Post-gamma-globulin
Size: 100ug
Code: CSB-PA06196A0G
Immunogen: Recombinant human Cystatin-C protein
Raised in: Goat
Species Reactivity: Human
Tested Applications: ELISA, WB, IHC
Application Notes:
Relevance: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
Clonality: Polyclonal
Isotype: lgG
Purity: CA-AS
Conjugate: Non-conjugated
Storage Buffer: PBS
Form: Liquid
Storage: Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
References: [1] "Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C."Abrahamson M., Grubb A., Olafsson I., Lundwall A.FEBS Lett. 216:229-233(1987) [2] "The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20."Saitoh E., Sabatini L.M., Eddy R.L., Shows T.B., Azen E.A., Isemura S., Sanada K. Biochem. Biophys. Res. Commun. 162:1324-1331(1989) [3] "Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases."Levy E., Lopez-Otin C., Ghiso J., Geltner D., Frangione B.J. Exp. Med. 169:1771-1778(1989)