Rabbit anti-Bovine Tumor necrosis factor polyclonal Antibody

Product Type: Polyclonal antibody
Product Name: Rabbit anti-Bovine Tumor necrosis factor polyclonal Antibody
Alias: Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a
Size: 100ug
Code: CSB-PA08474A0Rb
Species:
Immunogen: Recombinant Bovine Tumor necrosis factor protein
Raised in: Rabbit
Species Reactivity: Bovine
Tested Applications: ELISA, WB, IHC
Application Notes:
Relevance: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
References: [1] "Cloning of two members of the TNF-superfamily in cattle: CD40 ligand and tumor necrosis factor alpha."Mertens B.E.L.C., Muriuki M., Gaidulis L. Immunogenetics 42:430-431(1995) [PubMed: 7590981] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 50-233 (ISOFORM 1). Tissue: Blood. [2] "Rapid communication: single strand conformational polymorphism (SSCP) of bovine tumor necrosis factor alpha."Dietz A.B., Neibergs H.L., Womack J.E., Kehrli M.E. Jr.J. Anim. Sci. 75:2567-2567(1997) [PubMed: 9303477] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 91-193. Strain: Holstein.