Rabbit anti-Mouse C-X-C motif chemokine 11 polyclonal Antibody;FITC conjugated

Product Type: Polyclonal antibody
Product Name: Rabbit anti-Mouse C-X-C motif chemokine 11 polyclonal Antibody;FITC conjugated
Alias: Scyb11,Cxcl11,Interferon-inducible T-cell alpha chemoattractant,I-TAC,Small-inducible cytokine B11
Size: 100ug
Code: CSB-PA09289C0Rb
Immunogen: Recombinant Mouse C-X-C motif chemokine 11 protein
Raised in: Rabbit
Species Reactivity: Human
Tested Applications: ELISA, WB, IHC
Application Notes:
Relevance: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses .
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: FITC conjugated
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
References: [1] "Cloning, genomic sequence, and chromosome mapping of scyb11, the murine homologue of SCYB11 (alias betaR1/H174/SCYB9B/I-TAC/IP-9/CXCL11)."Meyer M., Erdel M., Duba H.C., Werner E.R., Werner-Felmayer G.Cytogenet. Cell Genet. 88:278-282(2000) [2] "The murine chemokine CXCL11 (IFN-inducible T cell alpha chemoattractant) is an IFN-gamma- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia."Widney D.P., Xia Y.-R., Lusis A.J., Smith J.B.J. Immunol. 164:6322-6331(2000)